Shenzhen OK Biotech Technology Co., Ltd. (SZOB)
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    Shenzhen OK Biotech Technology Co., Ltd. (SZOB)

    HK Ntxiv: 6 / F, Fo Tan Muaj Chaw, 26-28 Au Pui Wan St, Fo Tan, Shatin, Hongkong

    China mainland Ntxiv: 8F, Fuxuan Tsev, N ° 46, East Heping Rd, Longhua New District, Shenzhen, PRC China

    Email: nicole@ok-biotech.com

    smile@ok-biotech.com

    Web site: www.ok-biotech.com

    Tel: +852 6679 4580

> Tsev > Khoom > Kws > API > Cov ntsiab lus

Tolterodine Tartrate 124937-52-6

Tolterodine Tartrate 124937-52-6

Khoom hauj lwm DETROL ntsiav tshuaj muaj tolterodine tartrate. Lub moiety cum, tolterodine, yog ib tug muscarinic receptor antagonist. Tolterodine tartrate yog ib tug dawb, crystalline hmoov. Cov nqi no pKa yog cov 9.87 thiab cov solubility hauv dej yog 12 mg/mL. Nws yog soluble hauv methanol, soluble me ntsis nyob rau...

Hauj lwm yam khoom

Ntsiav tshuaj DETROL muaj tolterodine tartrate. Lub moiety cum, tolterodine, yog ib tug muscarinic receptor antagonist. Tolterodine tartrate yog ib tug dawb, crystalline hmoov. Cov nqi no pKa yog cov 9.87 thiab cov solubility hauv dej yog 12 mg/mL. Nws yog soluble hauv methanol, soluble me ntsis hauv ethanol, thiab

suab insoluble hauv toluene. Tus muab faib coefficient (cav D) n-octanol thiab dej yog 1.83 ntawm pH 7.3.

Kev txiav txim ntawm mechanism

CONTRACTION thiab salivation yog mediated ntawm cholinergic muscarinic receptors.

Tom qab no hauv lub qhov ncauj, tolterodine yog metabolized rau cov nplooj siab, uas ua rau cov

tus 5-hydroxymethyl derivative, ib feem coob uas muaj lub pharmacologically

metabolite. Metabolite 5-hydroxymethyl, uas exhibits ib yam antimuscarinic

zoo li cov tolterodine, contributes ho mus cov nyhuv tshuaj. Ob leeg

tolterodine thiab tus 5-hydroxymethyl metabolite muaj ib siab things rau muscarinic

receptors, vim neb ob leeg pom txoj kev negligible los yog affinity rau lwm neurotransmitter

receptors thiab lwm yam neeg cellular lub hom phaj, xws li cov calcium uas raws.

Tolterodine muaj ib pronounced ntxim rau cov zis muaj nuj nqi. Los rau urodynamic

tsis ua ntej thiab 1 thiab 5 teev tom qab ib qho 6.4 mg tolterodine tam sim

tso cai tau txiav txim rau kev noj qab nyob zoo tuaj pab dawb tau. Lub ntsiab los ntawm cov tolterodine ntawm 1 thiab 5

teev tau kev nce rau residual zis, reflecting tus tsis tag muab nchuav rau hauv

zis, thiab tus thawj hauv siab detrusor. Raws li cov kev tshawb pom muaj ib

nkaus antimuscarinic rau tus sab zais huam.

Sis tw kom zoo dua

1 zoo nrog kev sis tw nqe:

1) txuj: Enterprise txuj

(2) cov Purity = 98%

(3) peb muaj chaw tsim tshuaj paus thiab yuav muab cov khoom zoo Hoobkas nqe.

2 ceev thiab nyab xeeb tus me nyuam:

1) parcel tau muab xa hauv 24 teev tom qab them. Nrhiav zauv muaj

2) Secure thiab discreet cov zaub mov xa tuaj. Ntau cov chaw tsheb thauj mus los txoj kev rau koj xaiv.

3 peb muaj neeg thoob plaws lub ntiaj teb no:

1) kev pab thiab kev nplua nuj ua cov neeg muas zaub xav yooj yim nco, Tshuag tsim nyog thiab ceev tus me nyuam raws li lawv muaj siab.

2) kev ua lag luam tawm tswv yim thiab cov khoom tawm tswv yim yuav tau menyuam, ntsib cov neeg muas zaub #39; yuav tsum tau yog peb lub luag hauj lwm.

(3) zoo, sis tw nqi, tub ceev, first-class pab koj qhov nce lub koomhaum thiab qhuas los ntawm cov neeg muas zaub.


Hot Tags: tolterodine tartrate 124937-52-6, chaw tsim tshuaj paus, tsum, hoobkas, muas
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