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Cytomel / T3 (55-06-1)

Cytomel / T3 (55-06-1)

Liothyronine yog siv los kho cov hypothyroidism, ib qho mob uas qhov thyroid caj pas tsis tsim cov thyroid hormone txaus. Nws kuj yog siv los pab txo qhov loj ntawm qog cov qog qog (paub tias yog mus qhov quav) .Liothyronine kuj siv qee qhov kev kuaj mob los pab kuaj teebmeem nrog cov thyroid caj pas. Cov tshuaj no tsuas muaj nrog koj tus kws kho mob cov tshuaj.


1. Dab tsi yog Cytomel / T3 nyoos hmoov?

Liothyronine yog ib hom hluavtaws ntawm triiodothyronine (T3), thyroid hormone siv los kho cov tshuaj tiv thaiv hypothyroidism thiab myxedema coma. T3 yog cov thyroid hormone metabolically, uas ua rau kev tawm tswv yim, thiab lowers TSH qib. Nws nce cov metabolism hauv peripheral cov ntaub so ntswg thiab qhia thaum muaj kev puas tsuaj ntawm T4 rau T3 hauv cov ntaub so ntswg peripheral. Nws kuj yog siv los ua ib qho kev pabcuam zoo hauv kev kho kev nyuaj siab loj thaum siv nrog tshuaj tua kabmob (Antidepressants). Nws yog muag raws li ntsev sodium hauv lub npe ntawm Cytomel (lossis Tertroxin Australia).

 

Liothyronine yog thyroid hormone. Cov tshuaj hormone hormone yog cov natural lossis synthetic preparations uas muaj tetraiodothyronine (T4, levothyroxine) sodium los yog triiodothyronine (T3, liothyronine) sodium los yog ob qho tib si. T4 thiab T3 yog tsim nyob rau hauv tib neeg cov thyroid caj pas los ntawm iodination thiab coupling ntawm cov amino acid tyrosine. T4 muaj plaub lub xauv iodine thiab yog tsim los ntawm kev sib koom ua ke ntawm ob lub plhom ntawm cov npe ntawm dododotyrosine (DIT). T3 muaj peb qhov atoms ntawm iodine thiab yog tsim los ntawm qhov sib txuas ntawm ib lub qauv ntawm DIT nrog ib qho qauv ntawm monoiodotyrosine (MIT). Ob leeg cov roj ntsha muaj hauv cov thyroid colloid ua thyroglobulin. Cov tshuaj no tuaj yeem txhim kho cov tsos mob ntawm cov thyroid deficiency xws li qeeb, tsis muaj zog, hnyav nce, plaub hau poob, tawv nqaij, thiab hnov ​​mob khaub thuas. Nws kuj pab kho cov nqaij ntshiv (cov thyroid caj pas).

 

Cov tshuaj hormone hormone yog cov natural lossis synthetic preparations uas muaj tetraiodothyronine (T4, levothyroxine) sodium los yog triiodothyronine (T3, liothyronine) sodium los yog ob qho tib si. T4 thiab T3 yog tsim nyob rau hauv tib neeg cov thyroid caj pas los ntawm iodination thiab coupling ntawm cov amino acid tyrosine. T4 muaj plaub lub xauv iodine thiab yog tsim los ntawm kev sib koom ua ke ntawm ob lub plhom ntawm cov npe ntawm dododotyrosine (DIT). T3 muaj peb qhov atoms ntawm iodine thiab yog tsim los ntawm qhov sib txuas ntawm ib lub qauv ntawm DIT nrog ib qho qauv ntawm monoiodotyrosine (MIT). Ob leeg cov tshuaj hormones muaj nyob hauv cov thyroid colloid li tyroglobulin.


Cov tshuaj tiv thaiv cov thyroid hormone muaj rau ob pawg: (1) cov tshuaj hormonal preparations muab tau los ntawm cov tsiaj cov thyroid, thiab (2) cov tshuaj tua hluavtaws. Cov kev npaj ntuj tsim muaj xws li tsim tawm thyroid thiab thyroglobulin. Txaus siab rau cov thyroid yog muab los ntawm cov tsiaj nyeg uas yog siv rau khoom noj los ntawm txiv neej (nqaij nyug los yog nqaij hau), thiab thyroglobulin muab los ntawm cov qog ntawm qog. Lub Tebchaws Asmeskas Pharmacopeia (USP) tau qhia txog tag nrho cov ntsiab lus ntawm iodine ntawm natural preparations. Cov thyroid USP muaj tsawg dua (NLT) 0.17 feem pua ​​thiab tsis ntau tshaj (NMT) 0.23 feem pua ​​iodine, thiab thyroglobulin muaj tsawg dua (NLT) 0.7 feem pua ​​ntawm organically iodine. Cov ntsiab lus ntawm iodine tsuas yog ib qho kev qhia tsis ncaj ncees ntawm kev tshawb fawb txog kev mob bios.





 

2. Cytomel / T3 Ua Li Cas Cov Hmoov Phem ?  

Liothyronine yog siv los kho cov hypothyroidism, ib qho mob uas qhov thyroid caj pas tsis tsim cov thyroid hormone txaus. Nws tseem siv tau los pab txo qhov loj ntawm qog cov qog qog (paub tias yog mus qhov quav) .Liothyronine kuj siv qee qhov kev kuaj mob los pab kuaj teebmeem nrog cov thyroid caj pas. Cov tshuaj no tsuas muaj nrog koj tus kws kho mob cov tshuaj.


Cov kws kho mob yuav siv tau liothyronine hloov los yog ntxiv rau levothyroxine (T4) rau cov neeg mob uas siv cov thyroid hormone withdrawal. Thaum tus neeg mob tau thyroid cancer los yog Graves 'tus kab mob, ablation therapy nrog cov tshuaj iodine (131I) siv los tshem cov kab mob thyroid cov tawv nqaij uas yuav nyob rau tom qab thyroidectomy (phais kev phais ntawm caj pas). Rau qhov kev kho mob 131I yuav pab tau zoo, txoj kev siv cov thyroid tissue yuav tsum yog avid rau iodine, uas yog nce ntawm tus neeg mob TSH qib siab. Rau cov neeg mob uas tau noj cov tshuaj levothyroxine, TSH kuj yuav txhawb los ntawm kev txiav cov tshuaj levothyroxine rau 3-6 lub lis piam. Qhov ntev ntawm kev tshem tawm cov tshuaj hormone yuav tsum tau vim yog kev noj cov tshuaj lom ntev ib nrab, thiab yuav ua rau cov neeg mob hypothyroidism. Lub sij hawm luv luv ntawm liothyronine tso cai tawm ntawm ob lub lis piam, uas yuav txo tau cov tsos mob hypothyroidism. Ib qho povthawj yog mus ncua cov tshuaj levothyroxine, tom qab ntawd muab cov tshuaj liothyronine thaum T4 theem poob, thiab thaum kawg nres liothyronine ob lub lis piam ua ntej kev kho cov tshuaj iodine.


Liothyronine kuj tseem raug xaiv rau cov neeg mob uas muaj myxedema coma vim tias nws sai sai qhov pib ua thaum piv rau levothyroxine. Muaj qes-dose liothyronine tau pom tias yuav ua rau cov kev mob tshwm sim hauv cov neeg mob uas muaj cov thyroid ua haujlwm tsis muaj kev pab cuam txaus los ntawm lawv txoj kev nyuaj siab tom qab sim ntau yam antidepressants. Thaum lub sij hawm ntxiv rau cov tshuaj uas twb muaj lawm, liothyronine tau pab daws kev mob hauv 24% ntawm cov neeg mob uas koom rau hauv cov kab mob loj hauv STAR * Kev nyuaj siab ploj.Ua raws li ib xyoo 2001 kev ntsuas uas tau soj ntsuam cov txiaj ntsig ntawm kev ntxiv Liothyronine mus rau antidepressants, kev pab los ntawm Liothyronine.


Qhov nruab nrab ntawm qhov kev nyuab siab rau kev nyuaj siab yog 45 mcg ntawm Liothyronine txhua hnub, uas yog qis dua cov tshuaj siv rau kev kho mob hypothyroidism. Kwv yees li 9% ntawm cov neeg mob tsis noj cov tshuaj tiv thaiv liothyronine vim muaj kev phiv. Qhov txawv ntawm kev sib txawv ntawm txiv neej yuav yog vim qhov sib txawv hauv cov metabolism ntawm cov thyroid precursors.


Ib qho algorithm uas tsim los ntawm STAR * D lub rooj sibtham pom zoo li liothyronine raws li qhov kev xaiv thaum cov neeg mob tau ua txhaum ob yam tshuaj antidepressant.





3.Huaj Siv Tshuaj Cytomel / T3 nyoos twg?

Kev siv cov thyroid hormones yog txiav txim siab los ntawm qhov kev qhia thiab yuav tsum nyob rau hauv txhua txhua tus neeg raws li tus neeg mob cov lus teb thiab kuaj pom.


Cytomel (liothyronine sodium) Cov ntsiav tshuaj yog npaj rau kev siv lub qhov ncauj; ib zaug ib hnub twg yog qhov pom zoo. Txawm tias liothyronine sodium muaj kev txiav sai, nws cov teebmeem metabolic ua haujlwm rau ob peb hnub tom qab tsis tuaj yeem ua haujlwm.


Hauv kev txiav txim siab siv cov tshuaj, qhov kev pheej hmoo ntawm kev noj tshuaj yuav tsum raug txiav txim siab tiv thaiv qhov zoo uas nws yuav ua. Qhov no yog kev txiav txim siab koj thiab koj tus kws kho mob yuav ua. Rau cov tshuaj no, cov hauv qab no yuav tsum raug xam tias:


-Txhais koj tus kws kho mob yog tias koj tau muaj qhov tsis haum lossis tsis haum tshuaj rau qhov tshuaj no lossis lwm yam tshuaj. Thiab qhia rau koj tus kws paub txog kev noj qab haus huv yog tias koj muaj lwm yam kev ua xua, xws li cov khoom noj, cov khoom noj, cov khoom noj, lossis cov tsiaj. Rau cov khoom tsis yog tshuaj, nyeem cov ntawv sau los yog cov khoom xyaw kom zoo zoo.


Tus cev xeeb tub Ib tus US FDA, liothyronine yog categorised li Cev xeeb tub Qib A. Tus thyroid hormone yog kis tau rau me nyuam hauv plab los sis hauv plab, tiam sis txij thaum lub Kaum Hlis 2014, kev tshawb fawb tsis pom muaj teeb meem rau tus me nyuam hauv plab. Cov niam leej txiv yuav tsum siv cov thyroid hormone replacement therapy thoob plaws lub cev xeeb tub kom tsis txhob muaj cov txheej xwm phiv.


Kev Lom Zem Menyuam muaj qis tus nqi qis ntawm cov thyroid hormone, yog li nws yog qhov tseem ceeb rau kev ceev faj thaum pub niam mis thaum noj cov tshuaj huothyronine.

 

Cov neeg laus laus laus yuav tsum tau pib rau ntawm cov tshuaj qis liothyronine. Plasma (T3) nyob rau hauv cov pejxeem no muaj tsawg dua li 25% mus rau 40% .TXH yuav tsum tau saib xyuas txij thaum muaj kev pheej hmoo ntawm tus kab mob coronary artery, hyperthyroidism thiab cov pob txha ntau dhau los ntawm cov thyroid hloov tsis zoo lossis tsis txawv txav.





4. Txwv cov tshuaj Cytomel / T3 nyoos

Cov koob tshuaj no yuav txawv rau cov neeg mob txawv. Ua raws li koj tus kws kho mob cov lus txib lossis cov lus qhia ntawm daim ntawv lo. Cov ntaub ntawv hauv qab no xam nrog rau cov tshuaj no tsuas siv pes tsawg xwb. Yog tias koj koob txawv txawv, tsis txhob hloov nws tshwj tsis yog koj tus kws kho mob hais kom koj ua.


Tus nqi ntawm cov tshuaj uas koj noj yuav yog nyob ntawm lub zog ntawm cov tshuaj. Tsis tas li xwb, ntau npaum li cas koj noj txhua hnub, lub sij hawm tau tso cai ntawm cov tshuaj siv, thiab qhov ntev ntawm lub sij hawm koj noj cov tshuaj nyob ntawm qhov teeb meem kev kho mob uas koj siv cov tshuaj.


Liothyronine yog lub zog ntawm cov thyroid hormone. Raws li ntsev ntawm triiodothyronine (T3), nws zoo sib xws thiab pharmacologically sib npaug rau T3. Raws li xws li, nws ua rau lub cev kom nce cov kabmob metabolic rate, cuam tshuam rau protein synthesis thiab ua kom lub cev muaj zog rau catecholamines (xws li adrenaline) los ntawm permissiveness. Raws li monotherapy los yog kev sib xyaw nrog SSRIs, liothyronine kuj tseem tuaj yeem txhim khu ntawm cov hlab hlwb tshiab hauv lub hauv nruab nrab hauv lub paj hlwb. Cov thyroid hormones yog qhov tseem ceeb rau txoj kev loj hlob thiab kev sib txawv ntawm txhua lub hlwb ntawm tib neeg lub cev. Cov tshuaj hormones no kuj tswj cov roj ntsha, roj, thiab carbohydrate metabolism, uas cuam tshuam cov tib neeg hlwb siv cov keeb kwm zoo li cas.


Nyob rau hauv kev sib piv rau levothyroxine (T4), liothyronine muaj qhov pib ntawm qhov kev txiav txim zoo li lub sijhawm luv luv ntawm ib nrab ntawm lub neej, uas yog vim qe ntshav tsawg dua rau cov thyroxine-binding globulin thiab transthyretin.


Rau kev noj haus ntawm qhov ncauj (ntsiav tshuaj):

Rau kev kho mob me ntsis hypothyroidism:

Cov neeg laus-Thaum xub thawj, 25 micrograms (mcg) ib zaug ib hnub. Cov tshuaj tua kab mob yuav nce tau ntxiv txog 25 mcg txhua txhua 1 lossis 2 lub lis piam. Txawm li cas los xij, feem ntau yog tsis ntau tshaj 75 mcg ib hnub ib zaug.

Menyuam-Siv thiab koob tshuaj yuav tsum txiav txim los ntawm koj tus kws kho mob.


Rau kev kho mob ntawm myxedema:

Cov neeg laus-Thaum xub thawj, 5 mcg ib zaug ib hnub. Cov tshuaj tua kab mob yuav nce tau li ntawm 5 mus rau 10 mcg txhua txhua 1 lossis 2 lub lim tiam. Thaum twg txhua hnub ntawm 25 mcg mus txog, cov tshuaj ntau ntxiv yuav nce 5 mus rau 25 mcg txhua 1 lossis 2 lub lim piam raws li xav tau. Txawm li cas los xij, feem ntau yog tsis ntau tshaj 100 mcg ib hnub ib zaug.

Menyuam-Siv thiab koob tshuaj yuav tsum txiav txim los ntawm koj tus kws kho mob.


Rau kev kho mob ntawm congenital hypothyroidism:

Cov neeg laus thiab cov menyuam yaus hnub nyoog tshaj 3 xyoos -Yog siv thiab koob tshuaj yuav tsum tau txiav txim los ntawm koj tus kws kho mob.

Cov me nyuam-Thaum xub thawj, 5 mcg ib hnub ib zaug. Qog tshuaj tej zaum yuav nce 5 mcg txhua 3 lossis 4 hnub raws li xav tau.

Cov me nyuam muaj hnub nyoog 0 txog 1 xyoos ntawm-20 mcg ib hnub ib zaug rau kev zov me nyuam.

Cov me nyuam 1 txog 3 xyoos -50 mcg ib hnub ib zaug.


Rau kev kho mob ntawm yooj yim (non-toxic) goiter:

Cov neeg laus-Thaum xub thawj, 5 mcg ib zaug ib hnub. Cov tshuaj tua kab mob yuav nce tau li ntawm 5 mus rau 10 mcg txhua txhua 1 lossis 2 lub lim tiam. Thaum twg txhua hnub ntawm 25 mcg mus txog, yuav muab ntau npaum li cas ntxiv los ntawm 12.5 mus rau 25 mcg txhua 1 lossis 2 lub lim piam raws li xav tau. Txawm li cas los xij, feem ntau yog tsis ntau tshaj 75 mcg ib hnub ib zaug.

Menyuam-Siv thiab koob tshuaj yuav tsum txiav txim los ntawm koj tus kws kho mob.





5. Ceeb toom o Cytomel / T3 nyoos hmoov

Qee yam tshuaj yuav tsum tsis txhob siv los nyob ze los yog ib ncig ntawm lub sij hawm noj khoom noj los yog noj tej hom zaub mov vim tias kev sib tshuam yuav tshwm sim. Kev siv cawv lossis luam yeeb nrog qee yam tshuaj kuj tseem tuaj yeem ua rau sib cuam tshuam. Nrog koj tus kws kho mob tham nrog kev siv koj cov tshuaj nrog zaub mov, dej cawv, los yog luam yeeb.


Tshuaj nrog thyroid hormone kev ua si, ib leeg los yog ua ke nrog lwm cov tshuaj tiv thaiv, tau siv rau kev kho rog. Nyob rau hauv cov neeg mob euthyroid, koob tshuaj li ntawm txhua hnub ntawm cov tshuaj hormonal yuav tsum yog txo kom tsis txhob hnyav. Cov tshuaj hnyav loj dua tuaj yeem ua rau muaj mob hnyav los sis lub neej txawm tias yuav ua rau muaj kuab lom, tshwj xeeb tshaj yog thaum muaj kev sib koom nrog cov neeg uas muaj siab ntsws xws li kev siv rau lawv cov teebmeem anorectic.


Cov tshuaj nram qab no los yog cov moieties paub los cuam tshuam nrog kev ntsuam xyuas kuaj mob rau cov neeg mob hauv kev siv cov thyroid hormone therapy: androgens, corticosteroids, estrogens, qhov ncauj cov tshuaj tiv thaiv uas muaj estrogens, iodine-containing preparations thiab ntau cov tshuaj uas muaj salicylates.





6. Dab Tsi Ua Tuab Taws Teeb Meem Puas yog Cytomel / T3 raw hmoov ?

Liothyronine tej zaum yuav ua rau muaj ntau cov kev mob, feem ntau zoo xws li cov tsos mob ntawm hyperthyroidism, uas muaj xws li: [11]

 

poob phaus

tremor

mob taub hau

chim siab plab

ntuav

raws plab

lub plab cramps

nervousness

txob taus

insomnia

ntau hws

nce qab los noj mov

kub cev

Cov kev hloov hauv kev coj khaub ncaws

rhiab heev rau cua sov

 

Nws yog ib qho tseem ceeb heev uas koj tus kws kho mob xyuas koj kev nce qib hauv kev mus saib xyuas tas li. Qhov no yuav tso cai rau koj tus kws kho mob pom tias cov tshuaj ua haujlwm zoo thiab txiav txim siab seb koj puas yuav tsum tau noj tshuaj ntxiv. Yuav tsum kuaj cov ntshav thiab cov zis mus kuaj xyuas cov teeb meem tsis zoo.

 

Liothyronine yuav tsum tsis txhob siv los kho cov rog los yog lub hom phiaj ntawm kev poob phaus. Cov tshuaj no tsis muaj txiaj ntsig rau qhov hnyav hnyav thiab thaum uas tau npaum li cas, nws yuav ua rau muaj mob loj dua.

 

Hypothyroidism tuaj yeem ua rau cov txiv neej thiab cov poj niam ua tsis tau ntxiv. Liothyronine yuav tsum tsis txhob siv rau kev kho mob ntxiv lawm tshuav tshwj tsis yog tias yog los ntawm kev siv tshuaj tiv thaiv (hypothyroidism).


Hu rau koj tus kws kho mob sai li sai tau yog tias koj pib mob hauv siab, lub plawv dhia ceev ceev los yog tsis sib haum, kev tawm hws ntev, tsis muaj cua sov, tsis muaj zog, los yog lwm yam mob tsis zoo.


Rau cov neeg mob ntshav qab zib, nws yog ib qho tseem ceeb heev uas koj yuav tsum khiav ntawm koj cov ntshav los yog zis ntshav qab zib raws li koj tus kws kho mob qhia. Kuaj nrog koj tus kws kho mob tam sim ntawd yog tias koj pom tej yam pauv hauv koj cov ntshav qab zib.


Ib qho poob ntawm cov plaub hau tuaj yeem tshwm sim thaum thawj ob peb lub hlis dhau los ntawm kev kho tus mob liothyronine. Nug koj tus kws kho mob txog qhov no yog tias koj muaj kev txhawj xeeb





7. Muas Cytemol / T3   Raw hmoov Hm rom SZOB

Mus saib peb lub tsev muag tshuaj online thiab sau kom tiav cov tshuaj Cytomel / T3 raw khoom.

Paub →   Txhais qhov chaw ntawm tus me nyuam, qhov ntau ntawm qhov khoom thiab kev them nyiaj.

Paub →   Nyob rau lub sij hawm 30 feeb, koj yuav tau txais kev pom zoo ntawm koj daim ntawv txib.

Nws yuav xa tawm tsis pub dhau 12 teev.




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