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> Tsev > Khoom > Pharmaceutical > API > Cov ntsiab lus

Methandriol (521-10-8)

Methandriol (521-10-8)

Methandriol yog ib qho steroid uas zoo ib yam li 5-androdiol tsuas yog tias nws yog C-17 alpha alkylated thiab kuj esterified ntawm ob hnub. Nws yog tam sim no nrog ob peb lwm yam kev kho tshwj xeeb tshaj li cov uas tau tsim hauv teb chaws Australia. Hauv Dan Duchaine's Undertround Steroid phau ntawv II, Duchaine postulated tias methandriol tau kho qhov kev ua ntawm txhua yam steroid siv nrog nws. Nws tau hais tias methandriol tau ua li no los ntawm kev tuav pov hwm no heev uas ua rau SHBG ho knocking lwm lub steroids rau hauv lub xeev dawb thiab lub zog (zoo ib yam li tau piav rau mesterolone). Txawm hais tias methandriol khi rau SHBG, nws ua kom tsis muaj zog thiab tsis muaj peev xwm ua rau knocking ntau steroids tawm.


1. Dab tsi yog Methandriol nyoos hmoov?

Methandriol yog ib qho steroid uas zoo ib yam li 5-androdiol tsuas yog tias nws yog C-17 alpha alkylated thiab kuj esterified ntawm ob hnub. Nws yog tam sim no nrog ob peb lwm yam kev kho tshwj xeeb tshaj li cov uas tau tsim hauv teb chaws Australia. Hauv Dan Duchaine's Undertround Steroid phau ntawv II, Duchaine postulated tias methandriol tau kho qhov kev ua ntawm txhua yam steroid siv nrog nws. Nws tau hais tias methandriol tau ua li no los ntawm kev tuav pov hwm no heev uas ua rau SHBG ho knocking lwm lub steroids rau hauv lub xeev dawb thiab lub zog (zoo ib yam li tau piav rau mesterolone). Txawm hais tias methandriol khi rau SHBG, nws ua kom tsis muaj zog thiab tsis muaj peev xwm ua rau knocking ntau steroids tawm.

 

Methandriol yog heev rau aromatization (xws li androdiol) thiab nws tau raug pom tias nws tau khi ncaj qha mus rau cov tshuaj receptor tsis tas yuav tsum muaj kev aromatization. Thaum siv nrog lwm cov kab mob steriods kho, methandriol feem ntau yuav nyob hauv aromatase rau lub ntsiab lus hais tias lwm cov steroid tsis tuaj yeem ua rau aromatized cia nws nyob dawb thiab kom nquag plias. Thaum lub suab no zoo li ib lub tswv yim zoo thaum xub thawj, cov tshuaj estrogen ntau dhau los uas tau ntxiv los ntawm kev ntxiv tshuaj methandriol yuav ua rau kom muaj tus kabmob ginecomastia sai. Methandriol tau pom tias ua rau muaj zog ntawm 11-beta hydroxylase.Qhov no tshwm sim hauv cov pob zeb deoxycorticosterone, lub hwj chim mineralocorticoid uas ua rau lub cev tsis muaj ntsev thiab cov dej ua rau siab tuaj yeem ua rau kub ntxhov siab. Txoj kev kub ntxhov ntawm qhov kev kub ntxhov nrog methandriol yog nws pom Kev txo hwj chim ntawm 11-beta hydroxylase txo cov cortisol thiab ua rau txo qhov qis ntawm cov adrenals, kuj hu ua adrenal atrophy, uas tuaj yeem ua rau lub xeev ntawm lub cev tsis tuaj yeem ua tsis zoo rau kev tshem tawm ntawm kev siv tshuaj yuam kev uas inhibit 11-beta hydroxylase.

 

Methandriol metabolised mus rau methyltestosterone, estrogenic metabolites thiab 5-alpha txo androgens uas pab txhawb rau qhov profile zoo nkauj ntawm cov tshuaj steroid.Qhov "nce hauv kev ua haujlwm" tias qhov no steroid induces thaum siv nrog lwm androgens raws li npaj tau los ntawm Duchaine thiab lwm tus yuav muaj kev cuam tshuam rau kev txwv ntawm 11-beta hydroxylase uas yuav ua rau dej nce hnyav thiab ib qho anticatabolic los ntawm kev txo qis ntawm cov cortisol. Raws li tau hais hauv lwm qhov, qhov inhibition of 11-beta hydroxylase tuaj yeem ua rau kub siab thiab lwm yam tsis zoo los ntawm lub plawv.




 

2. Ua li cas Methandriol nyoos hmoov ua haujlwm?

Methandriol (los yog MAD) zoo li yog ib qho uas tsis tshua muaj thiab tsis pom qhov txawv ntawm anabolic steroids. Nws yog 5-androstenediol (5AD) uas tau hloov nws txoj kev hloov kho los ntawm kev ntxiv rau ib pawg methyl kom lub chaw sib xyaw es thiaj li ua tau tawg ntawm lub siab thaum siv lub ncauj lus. Qhov no tau zoo siv los ntawm lub cev thiab hu ua 17-alpha alkylation (17AA). Thawj qhov uas yuav tau hais yog qhov uas feem ntau nyiam cov cev nqaij daim tawv, cov leeg nqaij ntawm cov tshuaj. Nrog rau ib qho anabolic (mob leeg) ntawm 20-60 (piv tau testosterone uas muaj kev ntsuam xyuas ntawm 100 tus mob anabolic), tsis muaj ntau qhov nqaij nce siab tuaj yeem yuav tsum siv los ntawm MAD. Nws tseem yog me ntsis androgenic, dua thaum piv rau testosterone uas muaj cov nyhuv androgenic ntawm 100 MAD tsuas yog 30-60.


Methandriol tsis muaj zog thiab yuav muaj kev foom koob hmoov, thiab muaj ib qho kev foom koob hmoov, thiab ua rau nws tsis muaj kev txhawj xeeb uas tsis muaj kev txhawj xeeb los ntawm cov neeg tsis muaj kev txhawj xeeb uas muaj teeb meem ntawm prostate, plaub hau thiab pob txuv. Nws kuj siv tau los ntawm cov poj niam cev nqaij daim tawv uas xav kom tsis txhob muaj qhov phom sij ntawm androgens thaum lawv ua raws li qhov tsim nyog thiab qhov ntev li cas. Qhov ntawm qhov kev siv ntawm kev siv qhov ncauj thiab cov keeb neeg steroid yog ploj, muaj ib qho kev sib txheeb ntawm ib qho tshuaj thiab androgenic ntau ntau thiab kev muaj zog, cov kev phais thiab androgenic qis qis kuj yuav pab rau cov rog tsis zoo los ntawm kev thim nriav mus rau androgen reseptor (AR).




 

3. Siv cov tshuaj Methandriol nyoos hmoov ?  

Tshuaj Methandriol Dipropionate yog ib qho tshuaj tiv thaiv, ntseeg tau anabolic steroid nrog qee cov androgenic thaj chaw. Kev siv tshuaj rau Methandriol Dipropionate yog 100 mg txhua 2-3 hnub.

 

Los ntawm raising qib ntawm nitrogen retention, Methandriol Dipropionate stimulates protein synthesis, ua rau ntau dua nqaij pob; thiab nws nce lub zog. Tsis tas li ntawd, nws yuav muaj zog los tiv thaiv kab mob catabolic. Methandriol Dipropionate muaj zog txaus siv los ntawm tus kheej. Txawm li cas los xij, nws nquag siv nrog lwm txoj kev tuaj yeem los txhim kho cov teebmeem tag nrho. Methandriol dipropionate tsis ncaj qha mus hloov cov tshuaj estrogen, yog li nws muaj qis tshaj ntawm estrogen-phais kev phiv, xws li gynecomastia, dej retention, thiab roj deposition, uas feem ntau yog tsawg kawg yog tias lawv tshwm sim. Raws li Methandriol dipropionate muaj kev tivthaiv androgenic, cov kev phais thiab phais raug phais plab yog: oily tawv, pob txuv, cev plaub hau ntxiv, thiab tawv taub hau yog poob rau txiv neej txawv hau.

 




4. Txo nws cov phaj nyoos methandriol

Koob tshuaj rau cov kws ncaws pob yog 100mg hauv 2 rau 3 hnub. Qhov koob tshuaj pom zoo rau qhov ncauj ntawm Methandriol Dipropionate (MD) yog 40 mus rau 60mg ib hnub twg. Lub qhov ncauj yuav tsum tsis txhob noj ntau tshaj 6 lub lis piam.




 

5. Ceeb toom o f Methandriol nyoos hmoov

Methandriol niam txiv hormone 5AD tau pom tias yog ib qho "stemoid" uas muaj zog "estrogenic powers" (6), txij thaum methylation ua rau ntau yam bio-muaj thiab ua li no "muaj zog" Kuv ua kom ntseeg tias cov tshuaj methandriol estrogenic yog ntau zog tshaj 5AD . Qhov no tsuas yog ib qho xov xwm tsis zoo rau txhua tus Steriod.com cov neeg xav siv cov tshuaj no mus rau lub voj voog, cov tshuaj ua kom ntev li ntawm cov tshuaj yuav ua rau cov kua ntswg loj hlob ntawm cov txiv neej (gynecomastia), rog nce, dej tuav, poob ntawm kev sib deev, thiab sluggish natural testosterone ntau lawm. Qhov tseem ceeb tshaj yog 5AD nws tus kheej qhib lub tshuaj receptor (ER) (6) Qhov no yuav ua rau aromatize inhibitors zoo li cov tshuaj hurozole (femera) thiab anastrozole (arimidex) tsis tshua zoo rau kev tiv thaiv MAD cov tshuaj estrogenic vim tias nws tsis tas yuav raug aromatize enzyme kom ua kev puas tsuaj.


Ntau cov pov thawj uas txhawb MAD muaj cov tshuaj estrogenic ncaj nraim yog nws siv nyob rau hauv cov khoom ua rau tsiaj. Feem ntau yog siv los txhawb kev hnyav nce rau tsiaj txhu (7), kev tshawb fawb qhia ua ke nrog cov poj niam cev xeeb tub nrog poj niam (hormon, progesterone) txhawb qhov hnyav nce ntxiv uas yog ib leeg (8) -qhov nandrolone derivative trenbolone (9). MAD estrogenic cov cuab yeej yuav ua rau nws tseem ceeb nyob rau hauv no hais txog, qhov no yog vim li cas tiag MAD ntxiv rau lwm anabolic Veterinary preparations, tsis vim nws sensitizes tus AR Feem ntau ntawm cov profiles ntawm methandriol hais tias nws muab "loj zog lub zog", txawm li cas los saib lub pov thawj nws yuav zoo nkaus li qhov tsuas "qhov loj tshaj qhov tau txais" los ntawm MAD yuav qis los ntawm qhov nce ntxiv ntawm cov dej nyob hauv cov leeg nqaij uas yuav ua rau muaj kev cuam tshuam cov teebmeem thaum cov leeg nqaij sib khov thaum lub sij hawm qes ntawm qhov hnyav, zoo ib yam li qhov kev txiav txim ntawm lub tsho lub tsho.


Ntseeg los yog tsis estrogen yog ib leeg lub cev hormone zoo li, ua rau kev loj hlob los ntawm kev xa mus rau estrogen receptor ntawm cov leeg (10) cov no yog cov kev pab me me tiam sis tsis tsim nyog rau cov neeg sab nraud. Ib qho kev zoo nkauj los ntawm kev siv MAD yog nce ntshav siab (11) qhov no yuav yog los ntawm kev tuav dej ntawm vim yog kev ua pa lossis ua lwm yam hauv lub cev (11) Tsis muaj pov thawj tias methandriol tsis zoo rau cov roj cholesterol ces koj daim cardio vascular heath yuav qhov tsawg tshaj plaws ntawm koj kev txhawj xeeb yog tias koj xaiv los siv methandriol.




 

6. Dab Tsi Ua Tuab Taws Teebmeem tshwm sim los ntawm Methandriol?

Methandriol tsis ncaj qha aromatized los ntawm lub cev, tab sis ib qho ntawm nws paub metabolites yog methyltestosterone, uas tau aromatize. Methlyandrostenediol kuj ntseeg tau tias muaj qee yam kev ua tshuaj estrogenic. Nws yog, zoo li no, suav hais tias yog ib qho kev qaug zog rau cov mob estrogenic steroid. Gynecomastia tau ua tau thaum kho, tab sis feem ntau tsuas yog thaum siv ntau dua. Dej thiab rog rog kuj tuaj yeem ua teeb meem, dua nyob ntawm koob tshuaj. Cov neeg tsis paub qab hau yuav xav tau ntxiv cov tshuaj tiv thaiv no xws li Nolvadex® los txo cov kev mob tshwm sim.

 

Txawm hais tias feem ntau muab cais ua ib qho anabolic steroid, methylandrostenediol yog cov tshuaj yau thiab txaus. Cov kev phiv Androgenic phom sij yog sib txawv nrog cov tshuaj no. Qhov no tej zaum yuav muaj cov pob txha oily, pob txuv, thiab lub cev / lub ntsej muag plaub hau. Cov kab mob Anabolic / androgenic steroids kuj ua rau cov txiv neej cov plaub hau poob zuj zus. Cov poj niam raug ceeb toom ntawm cov virilizing cov teebmeem ntawm anabolic / androgenic steroids. Cov no kuj muaj xws li tob tob txog lub suab, cov poj niam cev nqaij daim tawv, kev hloov hauv daim tawv nqaij, kev loj hlob ntawm lub ntsej muag, thiab kev loj hlob. Nco ntsoov tias methylandrostenediol tsis raug cuam tshuam los ntawm 5-alpha reductase, yog li ntawd qhov tsis sib luag ntawm cov tshuaj steroid no tsis cuam tshuam los ntawm kev siv cov finasteride los yog dutasteride.

 

Methandriol yog ib qho c17-alpha alkylated compound. Txoj kev hloov no tiv thaiv kom tsis txhob siv tshuaj los ntawm daim siab, uas yog qhov feem pua ​​ntawm cov tshuaj nkag mus rau hauv cov ntshav hauv qab no. C17-alpha alkylated anabolic / androgenic steroids yuav ua tau hepatotoxic. Kev ncua ntev los yog raug ntau yuav ua rau lub siab puas. Hauv qee zaum kuj tseem yuav ua rau lub neej tsis muaj teeb meem. Nws yog ib qho tsim nyog kom mus ntsib kws kho mob ib ntus txhua lub sijhawm los saib xyuas lub siab ua haujlwm thiab kev noj qab haus huv. Txaus ntawm cov c17 alpha alkylated steriods qee feem ntau tsuas yog siv li 6-8 lub lim piam, kom mob siab tsis txhob mob siab ntxiv. Cov tshuaj ntawm cov tshuaj muaj peev xwm tuaj yeem mob me ntsis rau ntawm daim siab los ntawm kev tiv thaiv kab mob thawj zaug ntawm cov tshuaj noj, tab sis kuj tseem tuaj yeem tuaj yeem mob siab hepatotoxicity.




Kev siv lub siab ua kom tsis muaj zog ntxiv xws li daim siab mob Stabil, Liv-52, los yog Essentiale Forte thaum tab tom noj cov tshuaj hu ua hepatotoxic anabolic / androgenic steroids.

 

Cov kab mob Anabolic / androgenic steroids muaj peev xwm ua tau rau cov roj ntsha. Qhov no suav nrog txo cov HDL (zoo) roj cholesterol thiab ua rau LDL (phem) cov roj (cholesterol) qhov tseem ceeb, uas yuav hloov cov HDL mus rau LDL seem hauv cov kev coj ua uas muaj kev pheej hmoo siab ntawm kev mob arteriosclerosis. Qhov txheeb ze ntawm anabolic / androgenic steroid nyob rau hauv cov ntshav qab zib yog nyob ntawm qhov tshuaj, txoj kev ntawm txoj kev noj tshuaj (qhov ncauj thiab hauv tshuaj), hom steroid (aromatizable lossis non-aromatizable), thiab theem ntawm cov tshuaj tiv thaiv rau hepatic metabolism. Methylandrostenediol muaj cov nyhuv rau kev tswj cov roj cholesterol vim tias nws lub cev ua haujlwm tsis zoo rau lub siab puas ntsws thiab (nrog rau lub qhov ncauj) ntawm kev tswj hwm. Cov kab mob Anabolic / androgenic steroids kuj tuaj yeem cuam tshuam txog ntshav siab thiab cov ntshav triglycerides, txo qhov endothelial relaxation, thiab txhawb kev tu qab hlav qhov quav ntawm lub plab, tag nrho cov uas yuav ua rau muaj kab mob hauv lub plawv thiab cov mob plawv tsis zoo.

 

Pab kom txo cov kev mob plawv nws tau qhia kom muaj lub plawv dhia ua kom muaj zog thiab txo kom tsawg ntawm cov roj saturated, roj cholesterol, thiab yooj yim carbohydrates txhua lub sij hawm thaum muaj kev ua haujlwm AAS. Ntxiv nrog rau cov ntses roj (4 grams ib hnub) thiab ib hom mis cholesterol / antioxidant xws li Lipid Stabil lossis ib yam khoom uas muaj cov khoom sib piv uas tau zoo ib yam.

 

Tag nrho cov anabolic / androgenic steriods kho thaum siv cov tshuaj txaus los txhawb cov leeg nce hlwb yuav tsum suppress endogenous testosterone ntau lawm. Yog tias tsis muaj kev pabcuam ntawm cov tshuaj uas siv tshuaj tua cov qog, testosterone qib yuav tsum rov qab rau hauv li ntawm 1-4 lub hlis ntawm kev faib tshuaj. Nco ntsoov tias lub caij nyoog hypogonadotrophic hypogonadism yuav tsim tau theem siab rau kev tsim txom tsis ncaj, yuav tsum muaj kev cuam tshuam kev kho mob.

 

Cov kev mob tshwm sim saum toj no tsis suav nrog. Yog xav paub ntxiv txog kev phiv tshuaj, saib Steroid Side Effects page.




 

7. Yuav Methandriol Raw Hmoo f rom SZOB

Paub →   Mus xyuas peb lub tsev muag tshuaj online thiab sau cov ntawv xa tuaj ntawm Methandriol raw khoom.

Paub →   Txhais qhov chaw ntawm tus me nyuam, qhov ntau ntawm qhov khoom thiab kev them nyiaj.

Paub →   Nyob rau lub sij hawm 30 feeb, koj yuav tau txais kev pom zoo ntawm koj daim ntawv txib.

Nws yuav xa tawm tsis pub dhau 12 teev.




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